Which Drugs are Used for Seborrheic Dermatitis Treatment? 

The incidence of seborrheic dermatitis is about 1% to 3%, and the incidence of young people is 3% to 5%.Ketoconazole, Ciclopirox Olamine,Glucocorticoids,Pimecrolimus and Tacrolimus can be used for the treatment of Seborrheic dermatitis.

Seborrheic dermatitis is prone to recurrence and entanglement. The incidence of seborrheic dermatitis is about 1% to 3%, and the incidence of young people is 3% to 5%. Seborrheic dermatitis is also accompanied by severe itching.
At present, the main way to treat Seborrheic dermatitis are by controlling oil, antibacterial and  anti-inflammatory measures.
Controlling oil is the main way to treat Seborrheic Dermatitis daily.
  • It is necessary to reduce the intake of greasy food. In addition,it is suggested to take less spicy food. Although spicy food will not directly promote oil secretion, it may excite the autonomic nerves and indirectly promote the secretion of hair follicles and sebaceous glands.Meanwhile, it is suggested to take vitamin B properly, which can not only promote the repair of skin and mucous membranes, but also regulate and inhibit the secretion of fat.
Antibacterial medicine works well for the treatment of  Seborrheic Dermatitis. Below are the main medicines for clinical use.
  • Ketoconazole. Ketoconazole has antifungal properties and mediates inflammatory responses by inhibiting leukotriene production. It is reported that 2% ketoconazole foam gel (1 to 3.5 times a week for 4 months) or cream (2 to 3 times a week for 4 weeks) can significantly reduce facial Seborrheic Dermatitis symptoms. However, the disease often relapses significantly 2 to 4 weeks after treatment.
  • Ciclopirox Olamine.Ciclopirox Olamine is medicine with both antifungal and anti-inflammatory properties. It is reported that 1% Ciclopirox Olamine cream (once or twice a day for 28 days) is effective in reducing facial seborrheic dermatitis, which works better than 2% ketoconazole gel. Ciclopirox Olamine is available in various other formulations in different regions, such as 1% or 1.5% shampoo and 0.77% ointment.
Anti-inflammatory helps to relef the sypmtoms of Seborrheic Dermatitis.
  • Glucocorticoids. Glucocorticoids are widely used clinically for eborrheic Dermatitis treatment in short-term, but long-term use will cause adverse reactions.
  • eg: 1% hydrocortisone cream or 0.1% hydrocortisone butyrate ointment, triamcinolone acetonide chloramphenicol cream, 0.05% dexamethasone ointment, etc.
  • Note that the face and thin skin lesions should not be used for a long time to avoid local side effects of hormones.
  • Pimecrolimus. Pimecrolimus is a calcineurin inhibitor that inhibits the production of inflammatory cytokines. Studies have shown that pimecrolimus cream (1 to 2 times a day for 2 to 8 weeks) can improve the clinical symptoms and signs of facial seborrheic dermatitis.
  • Tacrolimus.Tacrolimus is also a calcineurin inhibitor that inhibits the transcription of inflammatory cytokines. Studies have shown the effectiveness of tacrolimus cream (twice daily for 12 to 24 weeks) in the treatment of seborrheic dermatitis.
Besides, If the itching is unbearable, antihistamines drugs can be used to relieve itching.
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